• Chris Johnson of Tennessee sets NFL-record for yards from scrimmage with 2,509 yards and became just the sixth player ever to rush for over 2,000 yards, with 2,006.
• Matt Schaub of Houston led the NFL in passing yards with 4,770. Finishing ahead of 2 Peyton Manning, 3 Tony Romo, 4 Aaron Rodgers and 5 Tom Brady.
• Andre Johnson of Houston led the league in receiving yards with 1,569.
• Adrian Peterson led the NFL with 18 Touchdowns
• The Indianapolis Colts finished with the best record, 14-2, despite losing their last two games.
• The San Diego Chargers finished with a 13-3 record, winning their final 11 games.